Package: denovolyzeR
Title: Statistical Analyses of De Novo Genetic Variants
Version: 0.1.0
Date: 2015-04-01
Authors@R: 
    c(
    person("James","Ware",email="j.ware@imperial.ac.uk",role=c("aut","cre")),
    person("Jason","Homsy",role="ctb"),
    person("Kaitlin","Samocha",role="ctb")
    )
Description: An integrated toolset for the analysis of de novo (sporadic) genetic sequence variants.  denovolyzeR implements a mutational model that estimates the probability of a de novo genetic variant arising in each human gene, from which one can infer the expected number of de novo variants in a given population size.  Observed variant frequencies can then be compared against expectation in a Poisson framework.  denovolyzeR provides a suite of functions to implement these analyses for the interpretation of de novo variation in human disease.
Depends: R (>= 3.1.0)
Imports: dplyr (>= 0.3), reshape (>= 0.8)
License: GPL-3
LazyData: true
Suggests: knitr
VignetteBuilder: knitr
URL: http://jamesware.github.io/denovolyzeR
BugReports: http://github.com/jamesware/denovolyzeR/issues
Packaged: 2015-04-09 06:35:00 UTC; jamesware
Author: James Ware [aut, cre],
  Jason Homsy [ctb],
  Kaitlin Samocha [ctb]
Maintainer: James Ware <j.ware@imperial.ac.uk>
NeedsCompilation: no
Repository: CRAN
Date/Publication: 2015-04-09 12:03:44
Built: R 3.1.3; ; 2015-04-10 08:00:48 UTC; unix
