Simulation of Time-to-Event Family Data and Penetrance Estimation

Documentation for package ‘FamEvent’ version 1.1

FamEvent-package	Family age-at-disease onset data simulation and penetrance function estimation
carrierprobgeno	Mutation carrier probabilities for individuals with missing genotypes conditional on observed genotypes
carrierprobpheno	Mutation carrier probabilities for individuals with missing gentoypes conditional on observed phenotypes and genotypes
penmodel	Estimate the penetrance model and penetrance curves
penmodelEM	EM algorithm for estimating the penetrance model with missing genotypes
penplot	Plot the penetrance function
plot.penmodel	Plot estimated penetrance curves from a model fit
plot.simfam	Plot pedigrees
simfam	Generate familial time-to-event data
summary.penmodel	Summary of a penetrance model fit
summary.simfam	Summary of simulated data