Enrichment Analysis of CRISPR/Cas9 Knockout Screen Data

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Documentation for package ‘sgRSEA’ version 0.1

Help Pages

melanoma808 A subset of CRISPR/Cas9 knockout screening data on melanoma cell lines
plotNScores Plot histograms of normalized gene scores
plotScores Plot histograms of gene scores
sgCount Generate a raw sgRNA read count table from fastq files
sgRSEA Perform a permutation test which computes gene scores and their significance
sgRSEA.mean Perform a permutation test similar to sgRSEA
TCnormalize Upper-quartile/total-count normalization of raw sgRNA read count data
UQnormalize Upper-quartile/total-count normalization of raw sgRNA read count data