cgd                package:bayesSurv                R Documentation

_C_h_r_o_n_i_c _G_r_a_n_u_l_o_m_a_t_o_u_s _D_i_s_e_a_s_e _d_a_t_a

_D_e_s_c_r_i_p_t_i_o_n:

     Dataset from Fleming and Harrington (1991).

     Data from a multicenter placebo-controlled randomized trial of
     gamma inferon in patients with chronic granulomatous disease
     (CGD). 128 patients were randomized to either gamma inferon (n=63)
     or placebo (n=65). For each patient the times from study entry to
     initial and any recurrent serious infections are available. There
     is a minimum of one and a maximum of eight (recurrent) infection
     times per patient, with a total of 203 records.

_U_s_a_g_e:

     data(cgd)

_F_o_r_m_a_t:

     a~data frame with 203 rows and 17 columns. There are the following
     variables contained in the data frame.

     _h_o_s_p_i_t code of the hospital

     _I_D case identification number

     _R_D_T date randomization onto study (mmddyy)

     _I_D_T date of onset of serious infection, or date the patient was
          taken off the study (mmddyy)

     _t_r_t_m_t treatment code, 1 = rIFN-gamma, 2 = placebo

     _i_n_h_e_r_i_t pattern of inheritance, 1 = X-linked, 2 = autosomal
          recessive

     _a_g_e age in years

     _h_e_i_g_h_t height of the patient in cm

     _w_e_i_g_h_t weight of the patient in kg

     _c_o_r_t_i_c_o using corticosteroids at time of study entry, 1 = yes, 2 =
          no

     _p_r_o_p_h_y using prophylatic antibiotics at time of study entry, 1 =
          yes, 2 = no

     _g_e_n_d_e_r 1 = male, 2 = female

     _h_c_a_t hospital category, 1 = US-NIH,  2 = US-other, 2 = Europe -
          Amsterdam, 4 = Europe - other

     _T_1 elapsed time (in days) from randomization (from sequence = 1
          record) to diagnosis of a serious infection or, if a censored
          observation, elapsed time from randomization to censoring
          date; computed as IDT - RDT (from sequence = 1 record)

     _T_2 0, for sequence = 1 record, if sequence > 1, T2 = T1(from
          previous record) + 1

     _e_v_e_n_t censoring indicator, 1 = non-censored observation, 2 =
          censored observation

     _s_e_q_u_e_n_c_e sequence number, for each patient, the infection recods
          are in sequence number order

_S_o_u_r_c_e:

     Appendix D.2 of Fleming and Harrington (1991).

_R_e_f_e_r_e_n_c_e_s:

     Fleming, T. R. and Harrington, D. P. (1991). _Counting Processes
     and Survival Analysis_. New York: John Wiley and Sons.

