BCG                  package:HSAUR                  R Documentation

_B_C_G _V_a_c_c_i_n_e _D_a_t_a

_D_e_s_c_r_i_p_t_i_o_n:

     A meta-analysis on the efficacy of BCG vaccination against
     tuberculosis (TB).

_U_s_a_g_e:

     data("BCG")

_F_o_r_m_a_t:

     A data frame with 13 observations on the following 7 variables.

     '_S_t_u_d_y' an identifier of the study.

     '_B_C_G_T_B' the number of subjects suffering from TB after a BCG
          vaccination.

     '_B_C_G_V_a_c_c' the number of subjects with BCG vaccination.

     '_N_o_V_a_c_c_T_B' the number of subjects suffering from TB without BCG
          vaccination.

     '_N_o_V_a_c_c' the total number of subjects without BCG vaccination.

     '_L_a_t_i_t_u_d_e' geographic position of the place the study was
          undertaken.

     '_Y_e_a_r' the year the study was undertaken.

_D_e_t_a_i_l_s:

     Bacille Calmette Guerin (BCG) is the most widely used vaccination
     in the world. Developed in the 1930s and made of a live, weakened
     strain of Mycobacterium bovis, the BCG is the only vaccination
     available against tuberculosis today. Colditz et al. (1994) report
      data from 13 clinical trials of BCG vaccine each investigating   
     its efficacy in the treatment of tuberculosis. The number of
     subjects  suffering from TB with or without BCG vaccination are 
     given here.  In addition, the data contains the values of two
     other  variables for each study, namely, the geographic latitude
     of the place where the study was undertaken and the year of
     publication. These two variables will be used to investigate and
     perhaps explain any heterogeneity among the studies.

_S_o_u_r_c_e:

     G. A. Colditz, T. F. Brewer, C. S. Berkey, M. E. Wilson, E.
     Burdick, H. V. Fineberg and F. Mosteller (1994), Efficacy of BCG
     vaccine in the prevention of tuberculosis. Meta-analysis of the
     published literature.  _Journal of the American Medical
     Association_, *271*(2), 698-702.

_E_x_a_m_p_l_e_s:

       data("BCG", package = "HSAUR")
       boxplot(BCG$BCGTB/BCG$BCGVacc, BCG$NoVaccTB/BCG$NoVacc,
               names = c("BCG Vaccination", "No Vaccination"), 
               ylab = "Percent BCG cases")

