ashina                 package:ISwR                 R Documentation

_A_s_h_i_n_a'_s _c_r_o_s_s_o_v_e_r _t_r_i_a_l

_D_e_s_c_r_i_p_t_i_o_n:

     The 'ashina' data frame has 16 rows and 3 columns. It contains
     data from a crossover trial for the effect of an NO synthase
     inhibitor on headaches. Visual analog scale recordings of pain
     levels were made at baseline and at five time points after
     infusion of the drug or placebo. A score was calculated as the sum
     of the differences from baseline. Data were recorded during two
     sessions for each patient. Six patients were given treatment on
     the first occasion and the placebo on the second. Ten patients had
     placebo first and then treatment. The order of treatment and the
     placebo was randomized.

_U_s_a_g_e:

     ashina

_F_o_r_m_a_t:

     This data frame contains the following columns:

     '_v_a_s._a_c_t_i_v_e' a numeric vector, summary score when given active
          substance.

     '_v_a_s._p_l_a_c' a numeric vector, summary score when given placebo
          treatment.

     '_g_r_p' a numeric vector code, 1: placebo first, 2: active first.


_S_o_u_r_c_e:

     Original data.

_R_e_f_e_r_e_n_c_e_s:

     M.Ashina et al. (1999), Effect of inhibition of nitric oxide
     synthase on chronic tension-type headache: a randomised crossover
     trial. _Lancet_ 353, 287-289

_E_x_a_m_p_l_e_s:

     plot(vas.active~vas.plac,pch=grp,data=ashina)
     abline(0,1)

