epileptic {glmmAK} | R Documentation

## Epileptic seizures

### Description

This data set considers information from a clinical trial of 59 epileptics, reported by Thall and Vail (1990). For each patient, the number of epileptic seizures was recorded during a baseline period of eight weeks. Patients were then randomized to treatment with the anti-epileptic drug progabide, or to placebo in addition to standard chemotherapy. The number of seizures was then recorded in four consecutive two-weeks intervals.

### Usage

    data(epileptic)

### Format

A data frame with 295 observations on the following 5 variables.

`id`
  a unique identifier for the subject in the study.
`seizure`
  a numeric vector giving the number of epileptic seizures.
`visit`
  a numeric vector giving the number of the visit, 0=baseline, and 1,2,3, and 4 for the four consecutive two-weeks intervals.
`trt`
  a numeric vector giving the treatment group.
`age`
  a numeric vector giving the age at the entry.

### Source

Thall, P. F., and Vail, S. C. (1990) Some covariance models for longitudinal count data with overdispersion. Biometrics, 46, 657–671.

### References

Breslow, N. E. and Clayton, D. G. (1993). Approximate inference in generalized linear mixed models. Journal of the American Statistical Association, 88, 9–25.

Kleinman, K. P. and Ibrahim, J. G. (1998). A semi-parametric Bayesian approach to generalized linear mixed models. Statistics in Medicine, 17, 2579–2596.

### See Also

`epilepticBC`

### Examples

    data(epileptic)
    ## maybe str(epileptic); plot(epileptic) ...

[Package glmmAK version 1.3-1 Index]