AP                  package:mratios                  R Documentation

_A_n_g_i_n_a _p_e_c_t_o_r_i_s _d_a_t_a

_D_e_s_c_r_i_p_t_i_o_n:

     A data set is generated (from normal distribution) to imitate the
     summary statistics in Table II of Bauer et al. (1998).  In the
     experiment, patients with chronic stable angina pectoris were
     randomized to five treatment arms (placebo, three doses of a new
     compound, and an active control). The primary endpoint is the
     difference in the duration of an exercise test before and after
     treatment.

_U_s_a_g_e:

     data(AP)

_F_o_r_m_a_t:

     A data frame with 303 observations on the following 2 variables.

     _p_r_e_p_o_s_t a numeric vector, the difference post treatment
          measurement minus pre treatment measurement

     _t_r_e_a_t_m_e_n_t a factor with levels AC (the active control), D0 (the
          zero dose, placebo), and D50, D100, D150, the three dose
          groups of the new compound.

_S_o_u_r_c_e:

     _Bauer, P., Roehmel, J., Maurer, W., and Hothorn, L. (1998)._
     Testing strategies in multi-dose experiments including active
     control. _ Statistics in Medicine 17, 2133-2146._

_E_x_a_m_p_l_e_s:

     library(mratios)

     data(AP)

     str(AP)

     boxplot(prepost ~ treatment, data=AP)
     by(AP,AP$treatment, function(x){mean(x$prepost)})
     by(AP,AP$treatment, function(x){sd(x$prepost)})

