panic {nparLD} | R Documentation |
Measurements of the degree of illness on a CGI scale for a group of patients suffering from panic disorder and agoraphobia.
data(panic)
Longitudinal data of 16 patients with CGI scores taken on 5 occasions.
A group of 16 patients from panic disorder and agoraphobia were treated with anti-depressant imipramin over a period of eight weeks. Measurements on a discrete scale of scores between 2 and 8 were taken (2=not ill through 8=extremely ill) on 5 occasions (0=baseline, 2=after two weeks, 4=after four weeks,...).
Brunner, E., Domhof, S., and Langer, F. (2002). Nonparametric Analysis of Longitudinal Data in Factorial Experiments,
Wiley, New York.
Brunner, E. and Langer, F. (1999). Nichtparametrische Analyse longitudinaler Daten, R. Oldenbourg Verlag, Munchen Wien.
## Analysis using LD-F1 design ## data(panic) var<-c(panic[,"W0"],panic[,"W2"],panic[,"W4"],panic[,"W6"],panic[,"W8"]) time<-c(rep(0,16),rep(2,16),rep(4,16),rep(6,16),rep(8,16)) subject<-rep(panic[,"Patient"],5) pat<-c(5,4,3,2,5) ex.f1<-ld.f1(var,time,subject,w.pat=pat,time.name="Week",description=FALSE) # Check that the order of the time level is correct. # Time level: 0 2 4 6 8 # If the order is not correct, specify the correct order in time.order. ## Wald-type statistic ex.f1$Wald.test # Statistic df p-value #Week 126.6946 4 0 ## ANOVA-type statistic ex.f1$ANOVA.test # Statistic df p-value #Week 36.93664 2.234135 0