Package: RefFreeEWAS
Type: Package
Title: EWAS using Reference-Free DNA Methylation Mixture Deconvolution
Version: 2.1
Date: 2017-02-20
Author: E. Andres Houseman, Sc.D.
Maintainer: E. Andres Houseman <eahouseman@gmail.com>
Depends: R (>= 3.2.2), isva, quadprog
Description: 
    Reference-free method for conducting EWAS while deconvoluting DNA methylation arising as mixtures of cell types.  
   The older method (Houseman et al., 2014,<doi:10.1093/bioinformatics/btu029>) is similar to surrogate variable analysis (SVA and ISVA), except that it makes additional use of a biological mixture assumption.
   The newer method (Houseman et al., 2016, <doi:10.1186/s12859-016-1140-4>) is similar to non-negative matrix factorization, with additional constraints and additional utilities.
License: GPL (>= 2)
NeedsCompilation: no
Packaged: 2017-02-25 20:49:14 UTC; housemae
Repository: CRAN
Date/Publication: 2017-02-25 23:57:36
Built: R 3.3.3; ; 2018-04-22 15:10:35 UTC; windows
